Simon Pegg and Nick Frost make a stop at the Little A’Lei’inn in Rachel, Nevada in the 2011 sci-fi movie Paul, which features an alien of the same name, so I had to check it out on my drive along the Extraterrestrial Highway.
I understand it was originally to be called the Little Ale Inn, but there was a mix-up with the sign. Since the area had recently been in the news with respect to UFOs, they rolled with the alien theme.